FIELD: medicine.;SUBSTANCE: to study the mechanisms of gastric cancer metastasis and to develop new methods for treatment of this pathology, epithelial-mesenchymal transformation of tumour epithelium is simulated by intragastric administration of 1 ml of a solution obtained by mixing 0.05% calcium carbonate suspension in 0.4% formaldehyde solution and 0.4% hydrogen peroxide solution at a 1:1 ratio to rats on day 1 and 3 of the experiment. The proposed method allows to model the epithelial-mesenchymal transformation of tumour epithelium at induction of experimental metastatic stomach cancer, after 4 months from the beginning of the experiment, in 83.3% of animals, and after 6 months - in all animals.;EFFECT: method improvement.;9 dwg, 1 ex
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机译：领域：医学;研究对象：为研究胃癌转移的机理并开发新的治疗方法，通过胃内注射1 ml混合0.05％钙获得的溶液，模拟肿瘤上皮的上皮-间质转化在实验的第1天和第3天以1：1的比例将碳酸盐悬浮在0.4％甲醛溶液和0.4％过氧化氢溶液中。所提出的方法允许在实验性转移性胃癌的诱导中，从实验开始的4个月后，在所有动物中的83.3％和6个月后-在所有动物中对肿瘤上皮的上皮-间质转化进行建模。方法改进。; 9 dwg，1 ex
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