Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucose-stimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans

C. Xiao; A. Giacca; A. Carpentier; G. F. Lewis

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Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucose-stimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans

机译：单不饱和，多不饱和和饱和脂肪摄入对超重和肥胖，非糖尿病人的葡萄糖刺激的胰岛素分泌，敏感性和清除率的差异作用

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摘要

Prolonged elevation of plasma specific fatty acids may exert differential effects on glucose-stimulated insulin secretion (GSIS), insulin sensitivity and clearance.

机译：血浆中特定脂肪酸的长期升高可能会对葡萄糖刺激的胰岛素分泌（GSIS），胰岛素敏感性和清除率产生不同的影响。

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来源
《Diabetologia》 |2006年第6期|1371-1379|共9页
作者
C. Xiao; A. Giacca; A. Carpentier; G. F. Lewis;
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作者单位

Departments of Medicine and Physiology University of Toronto;

Departments of Medicine and Physiology University of Toronto;

Department of Medicine Division of Endocrinology Sherbrooke University Hospital Sherbrooke University;

Departments of Medicine and Physiology University of TorontoToronto General Hospital;

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原文格式 PDF
正文语种 eng
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关键词
Insulin clearance; Insulin resistance; Insulin secretion; Lipotoxicity; Non-esterified fatty acids; NEFAs; Oral fat ingestion;

机译：胰岛素清除;胰岛素抵抗;胰岛素分泌;脂毒性;非酯化脂肪酸;NEFAs;口服脂肪摄入;

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1. Adverse effects on insulin secretion of replacing saturated fat with refined carbohydrate but not with monounsaturated fat: A randomized controlled trial in centrally obese subjects [J] . Chang Lin F., Vethakkan Shireene R., Nesaretnam Kalanithi, Journal of clinical lipidology . 2016,第6期

机译：用精制碳水化合物代替单不饱和脂肪代替饱和脂肪对胰岛素分泌的不良影响：中枢性肥胖受试者的随机对照试验
2. In vivo effects of polyunsaturated, monounsaturated, and saturated fatty acids on hepatic and peripheral insulin sensitivity [J] . Pereira Sandra, Breen Danna M., Naassan Anthony E., Metabolism: Clinical and Experimental . 2015,第2期

机译：多不饱和，单不饱和和饱和脂肪酸对肝脏和周围胰岛素敏感性的体内影响
3. The ingestion of saturated fatty acid triacylglycerols acutely affects insulin secretion and insulin sensitivity in human subjects [J] . Aldo V. Greco, Alessandro Bertuzzi, Antonino Scarfone, The British Journal of Nutrition . 2007,第6期

机译：摄入饱和脂肪酸三酰甘油会严重影响人类受试者的胰岛素分泌和胰岛素敏感性
4. Insulin secretion rate and 脽-cell sensitivity from oral glucose tolerance test in normotensive and normoglycemic humans [C] . Di Nardo, Francesco, Cerasa, Engineering in Medicine and Biology Society, 2006 Annual International Conference of the IEEE . 2006

机译：正常血压和正常血糖人群口服葡萄糖耐量试验的胰岛素分泌率和γ细胞敏感性
5. The effects of polyunsaturated fatty acids on immune function in obese insulin resistant rodents. [D] . Ruth, Megan Rebecca. 2008

机译：多不饱和脂肪酸对肥胖的胰岛素抵抗性啮齿动物免疫功能的影响。
6. Effects of Saturated Fat Polyunsaturated Fat Monounsaturated Fat and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials [O] . Fumiaki Imamura, Renata Micha, Jason H. Y. Wu, 2016

机译：饱和脂肪多不饱和脂肪单不饱和脂肪和碳水化合物对葡萄糖-胰岛素稳态的影响：随机对照喂养试验的系统评价和荟萃分析
7. Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucose-stimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans [O] . C. Xiao, A. Giacca, A. Carpentier, 2006

机译：单不饱和，多不饱和饱和脂肪摄入对葡萄糖刺激的胰岛素分泌，超重和肥胖，非糖尿病人类的敏感性和间隙的差异效应

Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucose-stimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans

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