Oral composition for use as a prophylactic, therapeutic and / or cosmetic agent for obesity / overweight in non-diabetic mammals, including humans and preparation of an oral composition.

摘要

"ORAL COMPOSITION FOR USE AS A PROPHYLATIC, THERAPEUTIC AND / OR COSMETIC AGENT FOR OBESITY / OVERWEIGHT IN NON-DIABETIC MAMMALS, INCLUDING PREPARATION OF AN ORAL COMPOSITION". The present invention relates to oral pharmaceutical compositions comprising an effective amount of a tungsten (VI) compound, preferably a tungstate salt, and more preferably sodium tungstate (Na2-WO4-4). which are useful for fighting obesity / overweight in non-diabetic mammals, including humans. The anti-obesity effect of sodium tungstate dihydrate on a rat model obesity-induced diet called a "canteen diet" was evaluated. These obese mice are a good model of non-diabetic obese mammals, including humans. The prophylactic, therapeutic and / or cosmetic treatment of obesity derived from this invention is surprising and, with respect to treatments previously proposed in the art, involves advantages such as efficacy, lack of toxicity, and relatively low price. Therefore, the oral compositions of the present invention are useful for the oral treatment of obesity / overweight in non-diabetic mammals, including humans.