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Insulin Acutely Inhibits Intestinal Lipoprotein Secretion in Humans in Part by Suppressing Plasma Free Fatty Acids

机译:胰岛素通过部分抑制血浆游离脂肪酸急性抑制人肠道小肠脂蛋白的分泌

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摘要

Intestinal lipoprotein production has recently been shown to be increased in insulin resistance, but it is not known whether it is regulated by insulin in humans. Here, we investigated the effect of acute hyperinsulinemia on intestinal (and hepatic) lipoprotein production in six healthy men in the presence and absence of concomitant suppression of plasma free fatty acids (FFAs).
机译:最近显示肠道脂蛋白的产生增加了胰岛素抵抗,但尚不清楚它是否受人体中胰岛素的调节。在这里,我们调查了存在和不伴随抑制血浆游离脂肪酸(FFA)的六名健康男性中急性高胰岛素血症对肠道(和肝脏)脂蛋白产生的影响。

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  • 来源
    《Diabetes》 |2010年第3期|p.580-587|共8页
  • 作者单位

    Mirjana Pavlic,1 Changting Xiao,1 Linda Szeto,1 Bruce W. Patterson,2 and Gary F. Lewis1From the 'Division of Endocrinology and Metabolism, Department of Medicine and Physiology. University of Toronto, Toronto, Canada, and the 2 Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.Corresponding author: Gary F. Lewis, gary.lewis@uhn.on.ca.Received 31 August 2009 and accepted 11 December 2009. Published ahead of print at http://diabetes.diabetesjournals.org on 22 December 2009. DOI: 10.2337/db09-1297.MP. and CX. contributed equally to this study.© 2010 by the American Diabetes Association, Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativeconunons.org/licenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with i8 U.S.C. Section i734 solely to indicale this fact.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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  • 入库时间 2022-08-17 13:45:37

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