The risk factors for acute respiratory distress syndrome in patients with severe acute pancreatitis

摘要

ABSTRACT:Acute respiratory distress syndrome (ARDS) is very common in patients with severe acute pancreatitis (SAP), the early interventions are essential to the prognosis of SAP patients. We aimed to evaluate the risk factors for ARDS in SAP patients, to provide insights into the management of SAP.SAP patients treated in our hospital from June 1, 2018 to May 31, 2020 were included. The characteristics and lab test results were collected and compared, and we conducted the logistic regression analyses were conducted to identify the potential risk factors for ARDS in patients with SAP.A total of 281 SAP patients were included finally, the incidence of ARDS in patients with SAP was 30.60%. There were significant differences on the respiratory rate, heart rate, APACHE II and Ranson score between 2 groups (all P??.05). Respiratory rate 30/min (odds ratio [OR]: 2.405, 95% confidence interval[CI]: 1.163-4.642), APACHE II score 11 (OR: 1.639, 95% CI: 1.078-2.454), Ranson score 5 (OR: 1.473, 95% CI: 1.145-2.359), polymorphonuclear 14?×?109/L (OR: 1.316, 95% CI: 1.073-2.328), C-reactive protein 150?mg/L (OR: 1.127, 95% CI: 1.002-1.534), albumin ≤30?g/L (OR: 1.113, 95% CI: 1.005-1.489) were the independent risk factors for ARDS in patients with SAP (all P??.05).The incidence of ARDS in SAP patients is relatively high, and it is necessary to carry out targeted early prevention and treatment for the above risk factors.Copyright ? 2021 the Author(s). Published by Wolters Kluwer Health, Inc.