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Applying the Fokker–Planck equation to grating-based x-ray phase and dark-field imaging

机译:将Fokker-Planck方程应用于基于光栅的X射线相和暗场成像

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X-ray imaging has conventionally relied upon attenuation to provide contrast. In recent years, two complementary modalities have been added; (a) phase contrast, which can capture low-density samples that are difficult to see using attenuation, and (b) dark-field x-ray imaging, which reveals the presence of sub-pixel sample structures. These three modalities can be accessed using a crystal analyser, a grating interferometer or by looking at a directly-resolved grid, grating or speckle pattern. Grating and grid-based methods extract a differential phase signal by measuring how far a feature in the illumination has been shifted transversely due to the presence of a sample. The dark-field signal is extracted by measuring how the visibility of the structured illumination is decreased, typically due to the presence of sub-pixel structures in a sample. The strength of the dark-field signal may depend on the grating period, the pixel size and the set-up distances, and additional dark-field signal contributions may be seen as a result of strong phase effects or other factors. In this paper we show that the finite-difference form of the Fokker-Planck equation can be applied to describe the drift (phase signal) and diffusion (dark-field signal) of the periodic or structured illumination used in phase contrast x-ray imaging with gratings, in order to better understand any cross-talk between attenuation, phase and dark-field x-ray signals. In future work, this mathematical description could be used as a basis for new approaches to the inverse problem of recovering both phase and dark-field information.
机译:传统上依赖于衰减以提供对比度的X射线成像。近年来,增加了两个互补方式; (a)相比之下,可以捕获难以使用衰减的低密度样本,以及(b)暗场X射线成像,其揭示了子像素样本结构的存在。可以使用晶体分析仪,光栅干涉仪或通过观察直接解决的网格,光栅或散斑图案来访问这三种模式。基于光栅和基于网格的方法通过测量照射中的特征在由于样品的存在而横向移动的差异来提取差分相位信号。通过测量结构化照明的可视性,通常是由于样品中的子像素结构的存在,通过测量暗场信号来提取暗场信号。暗场信号的强度可以取决于光栅周期,像素尺寸和设置距离,并且可以看出,由于强相位效应或其他因素,可以看到附加的暗场信号贡献。在本文中,我们示出了Fokker-Planck方程的有限差异形式可以应用于描述相位对比X射线成像的周期性或结构化照明的漂移(相位信号)和扩散(暗场信号)用光栅,为了更好地了解衰减,相位和暗场X射线信号之间的任何串扰。在未来的工作中,该数学描述可以用作恢复阶段和暗场信息的逆问题的新方法的基础。

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