Synthesis of Substituted 3,4-Dialkyl-2,6-Diaryl-Piperidin-4-ol Derivatives and Their Conformational Study

摘要

The synthesis of series of 3,4-dialkyl-2,6-diaryl-piperidin-4-ol derivatives(7-12)by reduction ofcis-3-alkyl-2,6-diarylpiperidin-4-one(1-6)using Grignard reagent has been reported. The synthesized heterocycles have been characterized on basis of spectroscopic data and their conformation has also been discussed.