with the corresponding radical values. Synthesis of compounds of the formula is carried out by reaction of compound of the formula with functional acid derivative of the formula Zo-COOH or by acylation of compound of the formula with compound of the formula . New intermediate compounds of the formulas and are proposed. Synthesized compounds were used as agents inhibiting cholecystokinin binding with receptors. Structure of compounds of the formulas , , , , and is given in description text. EFFECT: improved method of synthesis. 8 cl"/>
HETEROCYCLIC DERIVATIVES OF SUBSTITUTED 2-ACYLAMINO-5-THIAZOLES, METHODS OF THEIR SYNTHESIS, DERIVATIVE OF SUBSTITUTED 2-AMINOTHIAZOLE, DERIVATIVES OF 2-AMINO-4-PHENYLTHIAZOLE
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HETEROCYCLIC DERIVATIVES OF SUBSTITUTED 2-ACYLAMINO-5-THIAZOLES, METHODS OF THEIR SYNTHESIS, DERIVATIVE OF SUBSTITUTED 2-AMINOTHIAZOLE, DERIVATIVES OF 2-AMINO-4-PHENYLTHIAZOLE
HETEROCYCLIC DERIVATIVES OF SUBSTITUTED 2-ACYLAMINO-5-THIAZOLES, METHODS OF THEIR SYNTHESIS, DERIVATIVE OF SUBSTITUTED 2-AMINOTHIAZOLE, DERIVATIVES OF 2-AMINO-4-PHENYLTHIAZOLE
FIELD: chemistry of heterocyclic compounds. SUBSTANCE: product 1: heterocyclic derivatives of substituted 2-acylamino-5-thiazoles of the formula with the corresponding radical values. Synthesis of compounds of the formula is carried out by reaction of compound of the formula with functional acid derivative of the formula Zo-COOH or by acylation of compound of the formula with compound of the formula . New intermediate compounds of the formulas and are proposed. Synthesized compounds were used as agents inhibiting cholecystokinin binding with receptors. Structure of compounds of the formulas , , , , and is given in description text. EFFECT: improved method of synthesis. 8 cl
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机译:领域:杂环化合物的化学。物质:产品1:分子式为<图像文件=“ 00000001.GIF” he =“ 22” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 33” />的取代的2-酰基氨基-5-噻唑的杂环衍生物与相应的基本值。式的化合物的合成通过式,其官能酸衍生物为Z o Sup> -COOH或通过酰化公式公式。公式的新中间体化合物和。合成的化合物用作抑制胆囊收缩素与受体结合的药物。公式的化合物的结构,,<图像文件=” 00000010.GIF“ he =” 20“ imgContent =” undefined“ imgFormat =” GIF“ wi =” 28“ / >,<图像文件=“ 00000011.GIF” he =“ 22” imgContent =“未定义” imgFormat =“ GIF” wi =“ 28” />,<图像文件=“ 00000012.GIF” he =“ 20” imgContent = “ undefined” imgFormat =“ GIF” wi =“ 20” />和<图像文件=“ 00000013.GIF” he =“ 28” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 30” />在说明文字。效果:改进的合成方法。 8厘升
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