A Review on Quick Release mouth Dissolving film as a Convenient Dosage form for Oral delivery

摘要

For the preceding two decades, there has been a heightened demand for more patient-compliant dosage forms. Modern progresses in the technology have offered viable dosage substitutions from oral route for pediatrics, geriatric, bedridden, nauseous or noncompliant patients. Buccal drug delivery has newly become a chief route of drug administration. Numerous bio-adhesive mucosal dosage forms have been established, which includes adhesive tablets, gels, ointments, patches and more recently the usage of polymeric films for buccal delivery, also identified as mouth dissolving films. Due to fast dissolution it afford sooner onset of action, sidestepping the first pass metabolism, dropping gastric degradation and metabolism of drugs and thus enhance their oral bioavailability. These properties of oral films with patient convenience and compliance made prevalent and accepted dosage form for pediatric and geriatric as well as adult residents. The present review offers up to date review in fast dissolving oral films so investigators can easily track various technologies/research in design and development of oral fast dissolving film.