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Evaluation of Antibiotics Residues in Chicken Meat Samples in Lebanon

机译:黎巴嫩鸡肉样品中抗生素残留的评价

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Antibiotic residue in chicken is a human health concern due to its harmful effects on consumer health. This study aims at screening the antibiotic residues from 80 chicken samples collected from farms located in different regions of Lebanon. An optimized multi-class method for identification and quantification of 30 antibiotics from four different chemical classes (sulfonamides, tetracyclines, quinolones, and beta-lactams) has been developed by using liquid chromatography–mass spectrometry. The evaluation of antibiotics residues in 80 chicken muscles samples has shown that 77.5% of samples were at least contaminated with antibiotics residues, out of which 53.75% were exposed to co-occurrence of multidrug residues. The screening of the four antibiotics families has shown that ciprofloxacin (quinolones) represents the highest occurrence percentage (32.5%), followed by amoxicillin (β-lactams) (22.5%) and then tetracyclines (17.5%). Means of sarafloxacin, amoxicillin, and penicillin G residues levels were above the Maximum Residue Limit (MRL) recommended limit according to the European Union EC. This study revealed that chicken samples collected from Lebanese farms contain antibiotic residues. Guidelines for prudent use of antimicrobials agents for chicken should be adopted to reduce the prevalence of resistant Salmonella in chicken.
机译:由于其对消费者健康的有害影响,鸡肉中的抗生素残留是一种人类健康问题。本研究旨在从位于黎巴嫩不同地区的农场收集的80个鸡样本中筛选抗生素残留物。通过使用液相色谱 - 质谱法开发了一种优化的用于鉴定和定量30种不同化学类(磺胺酰胺,四环素,喹诺酮和β-内酰胺)的鉴定和定量30种抗生素的方法。在80只鸡肌肉样品中的抗生素残留物的评价表明,77.5%的样品至少污染抗生素残留物,其中53.75%暴露于多药物残留物的共发生。四种抗生素家族的筛查表明,环丙沙星(喹啉酮)代表最高的百分比(32.5%),其次是阿莫西林(β-内酰胺)(22.5%),然后四环素(17.5%)。 Sarafloxacin,Amoxicillin和青霉素G残留水平的方法高于欧洲联盟EC的最大残留限制(MRL)推荐限额。本研究表明,从黎巴嫩农场收集的鸡样本含有抗生素残留物。应采用谨慎使用抗微生物剂药物的指导原则,以减少鸡肉中抗性沙门氏菌的患病率。

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