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Stretta radiofrequency treatment vs Toupet fundoplication for gastroesophageal reflux disease: a comparative study

机译:STRETTA射频处理与胃食管反流性疾病的Toupet Goodplication:比较研究

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Outcomes of gastroesophageal reflux disease (GERD) using Toupet fundoplication (TF) and Stretta radiofrequency (SRF) have not been compared and this study was conducted to compare therapeutic efficacy of the two methods. This retrospective study analyzed a total of 230 patients undergoing TF or SRF at our hospital. Baseline data, reflux symptoms, the DeMeester scores, lower esophageal sphincter (LES) pressure and adverse events were compared over 1 year period. A total of 226 patients were included in the study. The time and frequency of reflux and percentage of reflux time before and 12?months after therapy were not significantly different. There were significantly interactions between the therapy method and follow-up time on the DeMeester score and LES pressure. Twelve months post therapy, the DeMeester score was significantly higher in SRF than in TF group, while the LES pressure was lower. At 12 months after therapy, multivariate Cox proportional regression analysis showed that reflux frequency, the DeMeester score and LES pressure were risk factors for poor prognosis in TF group, while reflux frequency and the DeMeester score, and LES pressure were risk factors for poor prognosis in SFR group. Compared with TF, SFR can significantly improve the esophageal pH and pressure in GERD patients without increasing the risk of poor prognosis.
机译:尚未比较胃食管反流疾病(GERD)的胃食管反流(GERD)和Stretta射频(SRF),并进行该研究以比较两种方法的治疗效果。本回顾性研究分析了我们医院的230例接受TF或SRF的患者。基线数据,回流症状,塞维斯特评分,1年后比较了较低的食管括约肌(LES)压力和不良事件。该研究中共有226名患者。回流的时间和频率和回流时间和12月12日的百分比治疗后的治疗后的数月没有显着差异。在搬运区和塞维斯特成绩上的治疗方法和随访时间之间存在显着的相互作用。治疗后12个月,搬运评分在SRF中比TF组显着高,而LES压力较低。在治疗后12个月,多元COX比例回归分析表明,回流频率,Demeester评分和LES压力是TF组预后差的危险因素,而回流频率和堤防得分,并且LES压力是预后不良的危险因素SFR组。与TF相比,SFR可以显着改善GERD患者的食管pH和压力,而不会增加预后差的风险。

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