Granular Cell Tumour: A Clinicopathological Study with Review of Literature

摘要

Granular Cell Tumours (GCTs) can occur in any part of the body. Many a times, they occur as a small swelling, clinically suspected to be a benign process. Histologically, they are characterised by the presence of cells with abundant granular cytoplasm.Aim: To study the clinicopathological spectrum of GCTs diagnosed.Materials and Methods: Data were collected from the archives of the Department of Pathology, on diagnosed cases of GCTs for a period of five years; from 2012 to 2017 and a total of 22 cases were included in the study. The slides, including special stains and Immunohistochemistry (IHC), whenever performed, were retrieved and studied. The results were tabulated and analysed.Results: In the present study 22 cases of GCT were described, commonly involving skin and subcutaneous tissue. Most of the lesions were less than a centimeter in size. Females were more often affected. On follow-up, no recurrence was noted.Conclusion: Granular cell tumours should be a part of the diagnostic differentials whenever lesions with granular cells are encountered.