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Prescribing Pattern ofAntifungal Medications at aTertiary Care Hospital in Oman

机译:阿曼三级护理医院的抗真菌药物处方模式

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Introduction: Inappropriate use of antifungal agents is implicated in the global burden of antifungal resistance, adverse outcomes like persistent infections, unnecessary exposure and increased cost. Data collection from time to time is to be done in order to have a check on the resistance/sensitivity pattern of the commonly prescribed antifungal drugs.Aim: To describe the pattern of antifungal drug prescription and administration to patients attending a university hospital in Oman.Materials and Methods: This was a descriptive, retrospective cross-sectional study conducted at Sultan Qaboos University Hospital (SQUH), a university hospital in Oman that covered the electronic patient's data for a period of one year (January 2013 to December 2013). The study included inpatients and outpatients of all ages and both genders attending SQUH and receiving antifungal medications at the study period. Frequencies and percentages were reported for categorical variables, while the mean and standard deviation were used to summarize the data for continuous variables.Results: A total of 1353 antifungal drug prescriptions were prescribed for 244 patients. More than half of all antifungal drug prescriptions were prescribed by haematology, infectious disease and family medicine departments. The majority of patients to whom these drugs were prescribed were diagnosed to have infectious diseases followed by prophylactic use in leukaemias and immunocompromised conditions. Fluconazole was the most commonly prescribed antifungal drug (n= 715, 52.8%) followed by nystatin and voriconazole (n=233; 17.2% and n= 152; 11.2%, respectively).Conclusion:This study will help in understanding antifungal prescription practices and help in directing future studies and also in developing local policies for appropriate use of antifungal drugs.
机译:简介:不当使用抗真菌剂会导致全球抗真菌耐药性负担,不良后果(如持续感染,不必要的接触和成本增加)。为了不时检查常用的抗真菌药物的耐药性/敏感性模式,需要不时进行数据收集。目的:描述抗真菌药物的处方模式以及对阿曼大学医院就诊患者的给药方式。资料和方法:这是在阿曼苏丹大学卡布斯大学医院(SQUH)进行的描述性,回顾性横断面研究,涵盖了电子病历一年(2013年1月至2013年12月)的数据。该研究包括所有年龄段的住院患者和门诊患者,以及在研究期间接受SQUH和接受抗真菌药物治疗的男女。报告分类变量的频率和百分比,同时使用均值和标准差汇总连续变量的数据。结果:244名患者共开出了1353份抗真菌药物处方。所有抗真菌药物处方中有一半以上是由血液学,传染病和家庭医学部门开具的。服用这些药物的大多数患者被诊断为感染性疾病,随后在白血病和免疫功能低下的情况下进行预防性使用。氟康唑是最常用的抗真菌药物(n = 715,52.8%),其次是制霉菌素和伏立康唑(分别为233; 17.2%和n = 152; 11.2%)。结论:本研究将有助于了解抗真菌处方并帮助指导今后的研究,并制定适当使用抗真菌药物的当地政策。

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