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首页> 外文期刊>The journal of thoracic and cardiovascular surgery >Survival and reoperation pattern after 20?years of experience with aortic valve–sparing root replacement in patients with tricuspid and bicuspid valves
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Survival and reoperation pattern after 20?years of experience with aortic valve–sparing root replacement in patients with tricuspid and bicuspid valves

机译:三尖瓣和双尖瓣瓣膜主动脉瓣保留根置换20年后的生存和再次手术模式

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ObjectiveRemodeling or reimplantation are established operative techniques of aortic valve–sparing root replacement. Long-term follow-up is necessary comparing tricuspid and bicuspid aortic valves.MethodsA total of 315 patients (tricuspid, n?=?225, bicuspid, n?=?89, quadricuspid, n?=?1; remodeling, n?=?101, reimplantation, n?=?214) were evaluated. Mean follow-up was 10.1?±?5.6 and 6.4?±?4.2?years for the remodeling and reimplantation group, respectively. Longest follow-up was 21.9?years with 99.2% completeness. Mean age of the patients was 55.9?±?14.3 for the remodeling group and 48.9?±?14.5?years for the reimplantation group.ResultsThere was no significant difference in survival between the remodeling and reimplantation group (P?=?.11). Survival was comparable with the normal population in the reimplantation group (P?=?.33). Risk factors for late death were age, diabetes, and a greater New York Heart Association classification. Cumulative incidence of reoperation at 10?years was 5.8% for the reimplantation and 11.7% for the remodeling group (P?=?.65). Overall, there was no difference in the cumulative incidence of reoperation between tricuspid and bicuspid aortic valve patients (P?=?.13); however, a landmark analysis showed that in the second?decade, the cumulative incidence of reoperation was greater in bicuspid aortic valve patients (P?ConclusionsThe remodeling and reimplantation aortic valve–sparing root replacement techniques provided excellent long-term survival. Although the number of patients was relatively small, we provide some hints that in the second?decade after the operation, especially in bicuspid aortic valve patients, the risk of reoperation may be increased, needing further evaluation.
机译:目的重塑或再植已成为主动脉瓣保留根置换的手术技术。方法比较三尖瓣和双尖瓣主动脉瓣的长期随访是必要的。方法共有315例患者(三尖瓣,n≥= 225,双尖,η≥89,四尖瓣,≥1,重塑,η=评估[101,再植入,n] = [214]。重塑组和再植入组的平均随访时间分别为10.1±5.6和6.4±4。2年。最长的随访时间为21.9年,完成率99.2%。重塑组患者的平均年龄为55.9±14.3岁,再植组的平均年龄为48.9±14.5岁。结果重塑组与再植组之间的生存期无显着差异(P?= ?. 11)。移植组的存活率与正常人群相当(P ==。33)。晚期死亡的危险因素是年龄,糖尿病和纽约心脏协会的更大分类。再植10年的再手术累积发生率,再植组为5.8%,重塑组为11.7%(P?= ?. 65)。总的来说,三尖瓣和双尖瓣主动脉瓣再手术的累积发生率没有差异(P ==。13)。然而,一项具有里程碑意义的分析表明,在第二个十年中,二尖瓣主动脉瓣膜切除术患者的再手术累积发生率更高(P?结论:重塑和再植入主动​​脉瓣膜保留根置换技术可提供出色的长期存活率。患者相对较小,我们提供一些提示,在术后第二个十年,尤其是在二尖瓣主动脉瓣膜患者中,再次手术的风险可能会增加,需要进一步评估。

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