Effects of scopoletin from noni fruit (Morinda citrifolia L.) to IL-10 levels in male white mice with hypersensitivity type I.

摘要

ABSTRACT A study about scopoletin activity on IL-10 levels of hypersensitivity type I male white mice has been conducted. The scopoletin was isolated from noni fruit (Morinda citrifolia L.) with soxhletation method using dichloromethane and purified by column chromatography method. Scopoletin was administered orally to hypersensitivity type I mice with dose variation 1, 3 and 10 mg/kg BW. After 24 hours of scopoletin administration, mice's blood was taken and amount of IL-10 was determined by E.