Effects of Flavonoids from Morus Alba Leaves Extract on Experimentally Induced Gastroesophageal Reflux Disease (GERD) In Rats

摘要

ABSTRACT The current study investigated the effect of standardized extract of Morus alba leaves on gastroesophageal reflux disease (GERD) in rats. The ethyl acetate fraction of Morus alba leaves (MAEF) in doses of 50, 100 and 200 mg/kg were administered orally twice daily for 5 days and omeprazole in the dose of 30 mg/kg one hour prior to the induction of disease. The gastric wall mucus level was increased (from 150.4.