Sobemovirus genome appears to encode a serine protease related to cysteine proteases of picornaviruses

摘要

>A putative serine protease was identified among non-structural proteins of southern bean mosaic virus (SBMV) by sequence comparison with cellular and viral proteases. The predicted SBMV proteased is played a significant similarity to cysteine proteases of picornaviruses, providing a possible evolutionary link between the two enzyme classes. It is suggested that SBMV follows the general expression strategy characteristic of other positive-strand RNA viruses containing 5′-terminal covalently linked proteins (VPg), i.e. generation of functional proteins by polyprotein processing.