286 Generation of a recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) with an antitumor activity in a variety of human cancer xenograft models

I.Goetsch; A.Gonzalez; A.Beck; J.F.Haeuw; N.Corvaia

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286 Generation of a recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) with an antitumor activity in a variety of human cancer xenograft models

机译：286在多种人类癌症异种移植模型中产生具有抗肿瘤活性的重组人源化抗胰岛素样生长因子受体I型抗体（h7C10）

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来源
《European Journal of Cancer Supplements》 |2004年第8期|共2页
作者
I.Goetsch; A.Gonzalez; A.Beck; J.F.Haeuw; N.Corvaia;
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中图分类肿瘤学;
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1. Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody H2Mab-41 Exerts Antitumor Activity in a Mouse Xenograft Model of Colon Cancer [J] . Yukinari Kato, Tomokazu Ohishi, Shinji Yamada, Monoclonal antibodies in immunodiagnosis and immunotherapy . 2019,第4期

机译：抗人表皮生长因子受体2单克隆抗体H2MAB-41在结肠癌的小鼠异种移植模型中施加抗肿瘤活性
2. Trastuzumab in combination with paclitaxel enhances antitumor activity by promoting apoptosis in human epidermal growth factor receptor 2-positive trastuzumab-resistant gastric cancer xenograft models [J] . Sei Shu, Yoriko Yamashita-Kashima, Mieko Yanagisawa, Anti-cancer drugs . 2020,第3期

机译：Trastuzumab与紫杉醇组合通过促进人表皮生长因子受体2阳性曲述抗性胃癌异种移植模型中的凋亡来增强抗肿瘤活性
3. Safety, tolerability, pharmacokinetics and antitumor activity of ganitumab, an investigational fully human monoclonal antibody to insulin-like growth factor type 1 receptor, combined with gemcitabine as first-line therapy in patients with metastatic pancreatic cancer: a phase 1b study. [J] . OkusakaT., IkedaM., FukutomiA., Japanese journal of clinical oncology. . 2014,第5期

机译：Ganitumab的安全性，耐受性，药代动力学和抗肿瘤活性，一种针对胰岛素样生长因子1型受体的研究性全人类单克隆抗体，结合吉西他滨作为转移性胰腺癌患者的一线治疗药物：1b期研究。
4. Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model [C] . Thinzar M. Lwin, Kentaro Miyake, Takashi Murakami, Molecular-Guided Surgery: Molecules, Devices, and Applications IV . 2018

机译：荧光人源化抗CEA抗体在源自患者的原位异种移植（PDOX）小鼠模型中特异性标记转移性胰腺癌
5. Cloning and expression of a biosimilar chimeric monoclonal antibody directed against the human epidermal growth factor receptor and its production in CHO cells for treatment of colo-rectal cancer. [D] . Motiwala, Hatim Maqbulhusen. 2012

机译：针对人表皮生长因子受体的生物仿制药嵌合单克隆抗体的克隆和表达及其在CHO细胞中的产生，用于治疗结肠直肠癌。
6. H2Mab-19 an anti-human epidermal growth factor receptor 2 monoclonal antibody exerts antitumor activity in mouse oral cancer xenografts [O] . Junko Takei, Mika Kato Kaneko, Tomokazu Ohishi, 2020

机译：H2mab-19抗人表皮生长因子受体2单克隆抗体在小鼠口腔癌异种移植物中施加抗肿瘤活性
7. A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts [O] . Liliane Goetsch, Alexandra Gonzalez, Olivier Leger, 2004

机译：重组人源化的抗胰岛素样生长因子受体类型I抗体（H7C10）增强了对人癌异种移植物的血红素和抗表皮生长因子受体治疗的抗肿瘤活性
8. Therapy of Prostate Cancer Using a Human Antibody Targeting the Type 1 Insulin-Like Growth Factor Receptor (IGF-IR) [R] . Plymate, S. R. 2009

机译：使用针对1型胰岛素样生长因子受体（IGF-IR）的人抗体治疗前列腺癌

286 Generation of a recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) with an antitumor activity in a variety of human cancer xenograft models

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