isolated monoclonal antibody, isolated human monoclonal antibody, pharmaceutical composition, isolated recombinant anti-igf-i and anti-igf-ii antibody or antigen-binding fragment thereof, method for detecting factor i and factor ii of human insulin growth in a sample , method for detecting human insulin growth factor i in a sample, isolated nucleic acid, recombinant cell, host cell, method for preparing an antibody, method for preparing an antibody, method for treating neoplastic disease in a mammalian individual, method for to diagnose neoplastic disease in a mammal and method to classify a drug candidate compound

摘要

ISOLATED MONOCLONAL ANTIBODY, ISOLATED HUMAN MONOCLONAL ANTIBODY, PHARMACEUTICAL COMPOSITION, ANTI-IGF-I AND ANTI-IGF-II RECOMBINANT ANTIBODY OR FRAGMENT OF BINDING THE ANTIGEN OF THE SAME, A HUMAN PROTECTION INTO THE HUMAN PROTECTION , METHOD FOR DETECTING HUMAN INSULIN GROWTH FACTOR I IN A SAMPLE, ISOLATED NUCLEIC ACID, RECOMBINANT CELL, HOST CELL, METHOD OF PREPARING AN ANTIBODY, METHOD OF PREPARING AN ANTIBODY, A METHOD OF METHOD FOR A TREATMENT DIAGNOSTIC NEOPLASTIC DISEASE IN A MAMMALIAN INDIVIDUAL AND METHOD FOR CLASSIFYING A CANDIDATE COMPOUND TO DRUG. Antibody compositions and methods for treating neoplastic diseases in a mammalian subject are provided. Methods of diagnosing cancer in an individual mammal are also provided.