Acute Encephalopathy and Pandemic (H1N1) 2009

摘要

To the Editor: Since the World Health Organization declared a global pandemic of in. uenza A pandemic (H1N1) 2009 in June 2009, the num-ber of cases of this strain of in. uenza has steadily risen. Although most cas-es have been mild, with complete and uneventful recovery, multiple cases of severe infection with complications, including death, have been reported. Yet the neurologic complications of this virus have been rarely described. We read with interest the article by Kitcharoen et al. (1) concerning a pa-tient with encephalopathy associated with pandemic (H1N1) 2009, which progressed to produce quadriplegia with diffuse sensory loss. In that study, however, pandemic (H1N1) 2009 virus was not isolated from the patient's ce-rebrospinal . uid (CSF) or brain tissue or detected by reverse transcription–PCR (RT-PCR). We report a case in an adolescent patient with encephal-opathy-associated pandemic (H1N1) 2009 that was confi rmed by real-time RT-PCR of CSF