Serum glucuronoxylomannan may be more appropriate for the diagnosis and therapeutic monitoring of Trichosporon fungemia than serum @b-d-glucan

摘要

With the increasing incidence of invasive trichosporonosis, this disease is now receiving more attention from physicians. Nakase et al. considered the elevation of serum (1–3)-β-d-glucan (BDG) levels a paradoxical sign for Trichosporon fungemia in patients with hematologic disorders.1 BDG is a fungal cell wall polysaccharide that is released into the bloodstream of patients in most invasive fungal infections (IFIs), with the exception of invasive zygomycosis and cryptococcosis. Until now, all relevant studies have only assessed the performance of BDG assays for the early diagnosis of IFIs in high-risk patients.