FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

D Agarwal; S Pineda; K Michailidou; J Herranz; G Pita; L T Moreno; M R Alonso; J Dennis; Q Wang; M K Bolla; K B Meyer; P Menéndez-Rodríguez; D Hardisson; M Mendiola; A González-Neira; A Lindblom; S Margolin; A Swerdlow; A Ashworth; N Orr; M Jones; K Matsuo; H Ito; H Iwata; N Kondo; M Hartman; M Hui; W Y Lim; P T-C Iau; E Sawyer; I Tomlinson; M Kerin; N Miller; D Kang; J-Y Choi; S K Park; D-Y Noh; J L Hopper; D F Schmidt; E Makalic; M C Southey; S H Teo; C H Yip; K Sivanandan; W-T Tay; H Brauch; T Brüning; U Hamann; A M Dunning; M Shah; I L Andrulis; J A Knight; G Glendon; S Tchatchou; M K Schmidt; A Broeks; E H Rosenberg; L J vant Veer; P A Fasching; S P Renner; A B Ekici; M W Beckmann; C-Y Shen; C-N Hsiung; J-C Yu; M-F Hou; W Blot; Q Cai; A H Wu; C-C Tseng; D Van Den Berg; D O Stram; A Cox; I W Brock; M W R Reed; K Muir; A Lophatananon; S Stewart-Brown; P Siriwanarangsan; W Zheng; S Deming-Halverson; M J Shrubsole; J Long; X-O Shu; W Lu; Y-T Gao; B Zhang; P Radice; P Peterlongo; S Manoukian; F Mariette; S Sangrajrang; J McKay; F J Couch; A E Toland; D Yannoukakos; O Fletcher; N Johnson; I dos Santos Silva; J Peto; F Marme; B Burwinkel; P Guénel; T Truong; M Sanchez; C Mulot; S E Bojesen; B G Nordestgaard; H Flyer; H Brenner; A K Dieffenbach; V Arndt; C Stegmaier; A Mannermaa; V Kataja; V-M Kosma; J M Hartikainen; D Lambrechts; B T Yesilyurt; G Floris; K Leunen; J Chang-Claude; A Rudolph; P Seibold; D Flesch-Janys; X Wang; J E Olson; C Vachon; K Purrington; G G Giles; G Severi; L Baglietto; C A Haiman; B E Henderson; F Schumacher; L Le Marchand; J Simard; M Dumont; M S Goldberg; F Labrèche; R Winqvist; K Pylk?s; A Jukkola-Vuorinen; M Grip; P Devilee; R A E M Tollenaar; C Seynaeve; M García-Closas; S J Chanock; J Lissowska; J D Figueroa; K Czene; M Eriksson; K Humphreys; H Darabi; M J Hooning; M Kriege; J M Collée; M Tilanus-Linthorst; J Li; A Jakubowska; J Lubinski; K Jaworska-Bieniek; K Durda; H Nevanlinna; T A Muranen; K Aittom?ki; C Blomqvist; N Bogdanova; T D?rk; P Hall; G Chenevix-Trench; D F Easton; P D P Pharoah; J I Arias-Perez; P Zamora; J Benítez; R L Milne

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FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

机译：FGF受体基因与乳腺癌易感性：乳腺癌协会联合会的结果

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Background:Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified FGFR2 as a breast cancer susceptibility gene. Common variation in other fibroblast growth factor (FGF) receptors might also modify risk. We tested this hypothesis by studying genotyped single-nucleotide polymorphisms (SNPs) and imputed SNPs in FGFR1, FGFR3, FGFR4 and FGFRL1 in the Breast Cancer Association Consortium.

机译：背景：乳腺癌是女性最常见的恶性肿瘤之一。全基因组关联研究已将FGFR2鉴定为乳腺癌易感基因。其他成纤维细胞生长因子（FGF）受体的常见变异也可能会改变风险。我们通过研究乳腺癌协会联合会中FGFR1，FGFR3，FGFR4和FGFRL1中的基因型单核苷酸多态性（SNP）和估算的SNP，验证了这一假设。

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1. Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study [J] . Roger L Milne, Mia M Gaudet, Amanda B Spurdle, Breast Cancer Research . 2010,第6期

机译：在乳腺癌协会联合会中评估常见遗传易感性变异，生殖史和体重指数与乳腺癌风险之间的相互作用：病例对照研究
2. Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium [J] . Lei Jieping, Rudolph Anja, Moysich Kirsten B., Human Genetics . 2016,第1期

机译：免疫抑制途径基因的遗传变异与乳腺癌易感性：来自乳腺癌协会协会的42,510例病例和40,577例对照的汇总分析
3. Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. [J] . Lambrechts D, Claes B, Vandorpe T, Human Molecular Genetics . 2011,第16期

机译：低外显率乳腺癌易感基因位点与特定的乳腺肿瘤亚型相关：乳腺癌协会联合会的发现。
4. Identification of Common and Unique Susceptibility Pathways Among Cancers of the Lung, Breast, and Prostate from Genome-Wide Association Studies and Tissue-Specific Protein Interactions [C] . David C. Qian, Jinyoung Byun, Younghun Han, International Molecular Medicine Tri-Conference. . 2015

机译：从基因组 - 宽协会研究和组织特异性蛋白质相互作用鉴定肺癌，乳腺癌和前列腺癌中共同和独特的易感性途径
5. Molecular stress signaling in breast epithelial cells: Characterization of the regulation of the breast cancer susceptibility gene 1 (BCRA1) by stress signaling, and, Design of an epidemiological study examining the effect of glucocorticoid receptor genetic variants on breast cancer risk [D] . Antonova, Lilia 2008

机译：乳腺上皮细胞中的分子应激信号传递：通过应激信号传递来表征乳腺癌易感基因1（BCRA1）的调节，以及一项流行病学研究的设计，旨在研究糖皮质激素受体基因变异对乳腺癌风险的影响
6. FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium [O] . D Agarwal, S Pineda, K Michailidou, 2014

机译：FGF受体基因与乳腺癌易感性：乳腺癌协会联合会的结果
7. FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium. [O] . Agarwal, D, Pineda, S, Michailidou, K, 2014

机译：FGF受体基因与乳腺癌易感性：来自乳腺癌协会联合会的结果。

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

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