A stereocontrolled total synthesis of (+/-) - khusimone. oligonucleotide synthesis.

摘要

A stereocontrolled total synthesis of (:t)-khusimone (1) has been successfully accomplished involving Wittig olefina- tion of the tricyclic ketone (17) as a key step. Intramolecular anionic cyclisation of the indane derivative (10) provided the tricyclic