Plasma Levels of the Proinflammatory Chitin-Binding Glycoprotein YKL-40, Variation in the Chitinase 3-Like 1 Gene (CHI3L1), and Incident Cardiovascular Events

摘要

Background YKL-40, encoded by the chitinase 3-like 1 (CHI3L1) gene, is a chitinase-like protein involved in innate immune function hypothesized to play a role in the progression of atherosclerosis that may have differential roles in myocardial infarction (MI), as compared to stroke.