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Clinical Effect of Human Embryonic Stem Cells Therapy in Two Cases of Cerebral Palsy

机译:人类胚胎干细胞疗法治疗脑瘫2例临床疗效

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Cerebral palsy (CP), a neurological disorder, has no known cure. The treatments with medicines, surgery and rehabilitation therapies may improve the child’s condition but satisfactory outcome has not yet been achieved. Human embryonic stem cells (hESCs) therapy has been used for the treatment of neurodegenerative and neurological disorders. Here we report findings of two patients suffering from CP, after undergoing treatment with hESC therapy. The treatment consisted of phases in which 0.25 mL (< 4 million cells) hESCs was administered through intramuscular route once daily and 1 mL of hESCs (< 16 million cells) was administered through intravenous route twice every 7 days. A marked improvement in cognitive and motor functions was seen in the patients after the treatment.J Neurol Res. 2015;5(3):230-232doi: http://dx.doi.org/10.14740/jnr338e
机译:脑瘫(CP)是一种神经系统疾病,目前尚无治愈方法。药物,手术和康复疗法可以改善孩子的病情,但尚未取得令人满意的结果。人类胚胎干细胞(hESCs)治疗已用于治疗神经退行性疾病和神经系统疾病。在此,我们报道了两名接受hESC治疗的CP患者。该治疗包括以下阶段:每天两次通过肌内途径给药0.25 mL(<400万个细胞)hESC,每7天两次通过静脉内途径给药1 mL的hESC(<1600万细胞)。治疗后患者的认知和运动功能明显改善。 2015; 5(3):230-232doi:http://dx.doi.org/10.14740/jnr338e

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