An Antibacterial Compound Isolated from Sponge-associated bacteria Rhodobacteracea bacterium

摘要

Information about antimicrobial compound derived from Rhodobacteraceae bacterium is not reported yet. The goal of this study was to get chemical structure of substance that play an important role inhibits pathogenic bacteria growth. The investigation of antibacterial compounds derived from ethyl acetate extract of Rhodobacteracea bacterium from Aaptos sp., was carried out and gave rise a new antibiotic lead compound. Ethyl acetate extract was run on normal phase open column and reverse phase high performance liquid chromatographies. High Resolution LC-Mass-Mass, 1D and 2D NMR were used to structural analysis. In this study, reported that Rhodobacteraceae bacterium that was isolated from sponge Aaptos sp., contained a new antibacterial compound N-benzyl-2-methoxy-N-(2-[4-nonylphenoxy]ethanamine. This compound was moderately inhibit against phatogenic Vibrio eltor , Bacillus subtilis and Staphylococcus aureus .