A Survey of Relationship Between Neonate and Mother Prognosis and Plasma Level of Blood Uric Acid in Preeclampsia Pregnant Women

摘要

The purpose of this study was investigated that whether the measure of the uric acid in pregnant women has cause-effect relationship with severity of preeclampsia, biochemical and urine parameters. This study was targeted the preeclampsia women with uric acid levels = 6 mg dL^-1 and -1 for comparing with healthy pregnant women. In order to survey of serum Hb, platelet, liver enzymes and renal function test findings, blood and urine samples of preeclampsia and healthy groups were taken before delivery and analyzed. There was significant differences in the gestational age and mean serum AST, ALT, BUN and urine albumin between preeclampsia groups and healthy women. Also the gestational age variable in preeclampsia women with uric acid levels = 6 mg dL^-1 were lower than preeclamptic patients who have lower than 6 mg dL^-1 uric acid . Systolic and diastolic blood pressure were higher in the both preeclampsia cases compared with control group. There was significant differences in Apgar scores in the first and fifth minutes of life between the preeclampsia groups and healthy women. Also Apgar score in the fifth minutes of life has a significant effect on the risk of preeclampsia with more than 6 mg dL^-1 uric acid compared with preeclampsia with less than 6 mg dL^-1 uric acid . Neonatal weight in the preeclampsia groups were lower than its levels in the control group. In conclusion our results declared that a cause-effect relationship between the secretion of serum uric acid and severity of preeclampsia, biochemical and urine parameters may in fact exist.