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A methodology for on‐board CBCT imaging dose using optically stimulated luminescence detectors

机译:使用光激发发光检测器进行机载CBCT成像剂量的方法

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Cone-beam computed tomography CBCT systems are used in radiation therapy for patient alignment and positioning. The CBCT imaging procedure for patient setup adds substantial radiation dose to patient's normal tissue. This study presents a complete procedure for the CBCT dosimetry using the InLight optically-stimulated-luminescence (OSL) nanoDots. We report five dose parameters: the mean slice dose ( D MSD ); the cone beam dose index ( CBDI W ); the mean volume dose ( D MVD ); point-dose profile, D(FOV); and the off-field Dose. In addition, CBCT skin doses for seven pelvic tumor patients are reported. CBCT-dose measurement was performed on a custom-made cylindrical acrylic body phantom (50 cm length, 32 cm diameter). We machined 25 circular disks (2 cm thick) with grooves and holes to hold OSL-nanoDots. OSLs that showed similar sensitivities were selected and calibrated against a Farmer-type ionization-chamber (0.6 CT) before being inserted into the grooves and holes. For the phantom scan, a standard CBCT-imaging protocol (pelvic sites: 125 kVp, 80 mA and 25 ms) was used. Five dose parameters were quantified: D MSD , CBDI W , D MVD , D(FOV), and the off-field dose. The D MSD for the central slice was 31.1 ± 0.85 mGy, and CBDI W was 34.5 ± 0.6 mGy at 16 cm FOV. The D MVD was 25.6 ± 1.1 mGy. The off-field dose was 10.5 mGy. For patients, the anterior and lateral skin doses attributable to CBCT imaging were 39.04 ± 4.4 and 27.1 ± 1.3 mGy, respectively.OSL nanoDots were convenient to use in measuring CBCT dose. The method of selecting the nanoDots greatly reduced uncertainty in the OSL measurements. Our detailed calibration procedure and CBCT dose measurements and calculations could prove useful in developing OSL routines for CBCT quality assessment, which in turn gives them the property of high spatial resolution, meaning that they have the potential for measurement of dose in regions of severe dose-gradients.PACS number(s): 87.57.-s, 87.57.Q, 87.57.uq
机译:锥形束计算机断层扫描CBCT系统用于放射治疗,以使患者对准和定位。用于患者设置的CBCT成像程序会向患者的正常组织增加大量的辐射剂量。这项研究提供了使用InLight光学激发发光(OSL)nanoDots进行CBCT剂量测定的完整程序。我们报告了五个剂量参数:平均切片剂量(D MSD);锥束剂量指数(CBDI W);平均体积剂量(D MVD);点剂量分布D(FOV);和场外剂量。另外,据报道有七名骨盆肿瘤患者的CBCT皮肤剂量。在定制的圆柱形丙烯酸人体模型(长度为50 cm,直径为32 cm)上进行CBCT剂量测量。我们加工了25个带有凹槽和孔的圆盘(2厘米厚)来固定OSL-nanoDots。选择具有相似灵敏度的OSL,然后将其插入Farmer型电离室(0.6 CT)进行校准,然后将其插入凹槽和孔中。对于幻像扫描,使用标准的CBCT成像协议(骨盆部位:125 kVp,80 mA和25 ms)。量化了五个剂量参数:D MSD,CBDI W,D MVD,D(FOV)和场外剂量。中心切片的D MSD在16 cm FOV时为31.1±0.85 mGy,CBDI W为34.5±0.6 mGy。 D MVD为25.6±1.1 mGy。场外剂量为10.5 mG​​y。对于患者而言,可归因于CBCT成像的前,外侧皮肤剂量分别为39.04±4.4和27.1±1.3 mGy.OSL nanoDots方便用于测量CBCT剂量。选择nanoDots的方法大大降低了OSL测量的不确定性。我们详细的校准程序以及CBCT剂量测量和计算可以证明对开发OSB例程进行CBCT质量评估非常有用,这反过来又赋予了它们高空间分辨率的特性,这意味着它们有可能在重剂量区域测量剂量,梯度.PACS编号:87.57.-s,87.57.Q,87.57.uq

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