Tetrahydroisoquinolic acid derivatives from the seeds of Mucuna pruriens Baker

摘要

A tetrahydroisoquinolic acid glycoside identified as 1,1-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroxyisoquinolin-3- oic acid α-6-β-D-galactopyranosyl-(1→2)-β-D-galactopyrano- side (mucunatetrahydroisoquinolinic acid digalactoside) and n-tetracosan-1, 15 β -diol (mucunatetracosandiol) have been isolated as new phytoconstituents from the seeds of Mucuna pruriens Baker (Papilionaceae) along with the known compounds n-henetriacontane, 1,1- dimethyl-1,2,3,4-tetrahydroisoquinoline-3-oic acid, β-sitosterol and its β-D-glucopyranoside. The structures of all the isolated compounds have been elucidated on the basis of spectral data analyses and chemical reactions