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Gastro retentive Drug Delivery Systems: A Review

机译:Gastro保持性药物递送系统:综述

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In recent years scientific and technological advancements have been made in the research and development of controlled release oral drug delivery systems by overcoming physiological adversities like short gastric residence times and unpredictable gastric emptying times. Floating tablets are the systems which are retained in the stomach for a longer period of time and thereby improve the bioavailability of drugs. Floating tablets were prepared using directly compression technique using polymers like HPMC K4M HPMC K15M and HPMCK100M for their gelforming properties.
机译:近年来,通过克服诸如短胃停留时间和不可预测的胃排空时间的生理逆境,在控释口服药物递送系统的研究和开发中已经取得了科学和技术上的进步。漂浮片剂是在胃中保留较长时间,从而提高药物生物利用度的系统。使用直接压缩技术,使用诸如HPMC K4M,HPMC K15M和HPMCK100M之类的聚合物来制备浮片剂,因为它们具有凝胶化特性。

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