Papiller Tiroid Mikrokarsinomunun Nadir G?rülen Klinik Seyri; Akci?er ve Kemik Metastaz?

摘要

Papillary thyroid microcarcinomas are slow-growing tumours; distant metastases causing mortality is very rare. Case presentation We report the case of a 35-year-old woman with lung and bone metastases of a multifocal papillary thyroid microcarcinoma (PTMC). She had undergone a subtotal thyroidectomy due to euthyroide multinodular goitre without fine needlle aspiration biopsy. Iodine-131-whole body scan showed markedly iodine retention in the neck, lung and pelvis. Chest computed tomography (CT) and Pelvic magnetic resonance imaging (MRI) confirmed metastases in the lung and ischium pubis. She underwent completion thyroidectomy and bilateral neck dissection. She is going to have high dose radioactive iodine ablation therapy after resection of bone metastases. Conclusion: It should be considered that patients with papillary microcancer can rarely show agressive clinic. Turk Jem 2011; 15: 20-2 ?zet Papiller tiroid mikrokarsinomu yava? büyüyen bir tüm?r olup; uzak metastaza ba?l? ?lüm ?ok nadirdir. Vaka sunumu 35 ya??nda papiller tiroid mikrokarsinomu olan, akci?er ve kemik metastazl? bayan hastay? sunduk. Hastaya tiroid ince i?ne aspirasyon biyopsisi yap?lmaks?z?n ?tiroid multinodüler guatr nedeni ile subtotal tiroidektomi uygulanm??t?. ?yot -131 ile yap?lan tüm vücut iyot taramada pelvis, akci?er ve boyunda belirgin olarak iyot tutulumu izlendi. Akci?er bilgisayarl? tomografisi ve pelvis manyetik rezonans g?rüntüleme ile akci?er ve iskium pubisdeki metastazlar do?ruland?. Hastaya tamamlay?c? tiroidektomi ve bilateral boyun disseksiyonu uyguland?. Kemik metastaz?n?n ??kar?lmas?ndan sonra yüksek doz iyot 131 tedavisi verilmesi planland?. Sonu? Papiller mikrokanserli hastalar?n nadirde olsa agresif klinik seyir g?sterebilece?i g?z ?nünde bulundurulmal?d?r. Türk Jem 2011; 15: 20-2