首页> 外文期刊>Post?py Higieny i Medycyny Do?wiadczalnej >Aflatoksyny – charakterystyka i wp?yw na zdrowie cz?owieka
【24h】

Aflatoksyny – charakterystyka i wp?yw na zdrowie cz?owieka

机译:黄曲霉毒素-特征及其对人体健康的影响

获取原文

摘要

Some molds commonly occurring in the natural environment produce mycotoxins in the process of secondary metabolism. Aspergillus flavus and A. parasiticus are species of molds, which are responsible for the production of aflatoxins and are crucial in the pathogenesis of human diseases. Aspergillus species present in decaying plants, the soil and their spores are transferred via air currents and insects to crops and food storages. Aflatoxins B1, B2, G1, G2, M1 and M2 are the most common derivatives of aflatoxins. Ingestion of contaminated food is the main source of exposure to aflatoxins, which adversely affect the health of both humans and animals. The compounds can cause acute or chronic toxic effects of a teratogenic, mutagenic, carcinogenic, immunotoxic or hepatotoxic character. Molecular aflatoxins affect DNA mutations, postranslation peptids chains modification, proteins and nucleic acids methylation and the formation of free radicals.Due to aflatoxins carcinogenic features and frequent occurrence in food and forages they are routinely examinated in some groceries and agricultural products.
机译:自然环境中常见的一些霉菌在次级代谢过程中会产生霉菌毒素。黄曲霉和寄生曲霉是霉菌的种类,它们负责黄曲霉毒素的产生,在人类疾病的发病机理中至关重要。腐烂植物中存在的曲霉菌种,土壤及其孢子通过气流和昆虫转移到农作物和食物储存库中。黄曲霉毒素B1,B2,G1,G2,M1和M2是黄曲霉毒素最常见的衍生物。摄入受污染的食物是接触黄曲霉毒素的主要来源,黄曲霉毒素会对人类和动物的健康产生不利影响。该化合物可引起致畸,诱变,致癌,免疫毒性或肝毒性的急性或慢性毒性作用。分子黄曲霉毒素会影响DNA突变,正翻译肽链修饰,蛋白质和核酸甲基化以及自由基的形成。由于黄曲霉毒素的致癌特性以及在食品和饲料中的频繁发生,它们经常在某些杂货和农产品中进行检测。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号