Invest in the future - Oepa based chemotherapy for childhood Hodgkin lymphoma with minimal supportive care and late toxicity

摘要

Hodgkin lymphoma displays characteristic epidemiological, clinical and pathological features in different geographical areas. Objective was to analyze demographic profile, disease characteristics, event free survival (EFS), overall survival (OS) and risk factors for relapse in patients with Hodgkin lymphoma (HL) treated with chemotherapy only protocols. Background: The management of childhood Hodgkin Lymphoma has been a success story in oncology with long term survival rates of more than 90%. This has been made feasible by various co-operative group trials that have tailored therapy .It is imperative to reduce both acute and late effects of therapy to enable intact survival. We present our data on the efficacy and safety profile of hybrid protocol in these children over the past 15 years.