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Otomycosis; clinical features, predisposing factors and treatment implications

机译:牙菌病;临床特征,诱发因素和治疗意义

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Objectives: The aim of this study was to determine the frequency of otomycosis, the clinical presentation, predisposing factors and treatment outcomes.Methods: This observational study was conducted at ENT department of Combined Military Hospital Attock, from October, 2010 to September, 2012. Convenient sample comprising 180 patients of both sexes and all age groups were selected from ENT OPD. The frequency, predisposing factors and most common symptoms of otomycosis were recorded. The response to different antifungal agents was also observed. Results were recorded in percentages.Results: There were 180 patients with documented diagnosis of otomycosis. There were 107 (59%) males and 73 (41%) females. The age of patients ranged from 1? years to 75 years with a mean age of 38.5 years. Mean follow up time was 2 years. Most common presenting symptom was hearing loss (77.7%) followed by pruritis (68.8%) and otalgia (40%). We prescribed 1% clotrimazole drops or lotion in 58% patients and 2% salicylic acid in 31% cases. Both of these agents are effective. Topical 1% clotrimazole drops yielded highest resolution rate with lowest recurrent rate. Overall 149 (83%) patients were improved with initial treatment and 31 (17%) did not respond to initial treatment. Eight (4.4%) patients had a history of otological procedures. Four (2.2%) patients had canal wall down procedures that resulted in mastoid cavity. To analyse the efficacy of 1% clotrimazole and 2% salicylic acid we applied Z-Test to calculate the difference between 2 proportions of patients before treatment with those patients who remained uncured after treatment.Conclusion: Otomycosisis commonly presented with decreased hearing, pruritis, otalgia & otorrhoea. It usually resolves with local toilet of ear and instillation of antifungal agents. Eradication of disease is difficult in presence of a mastoid cavity and metabolic diseases like diabetes mellitus.doi: http://dx.doi.org/10.12669/pjms.303.4106How to cite this:Anwar K, Gohar MS. Otomycosis; clinical features, predisposing factors and treatment implications. Pak J Med Sci 2014;30(3):564-567. doi: http://dx.doi.org/10.12669/pjms.303.4106This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
机译:目的:本研究的目的是确定耳菌病的发生频率,临床表现,诱发因素和治疗结果。方法:本观察研究于2010年10月至2012年9月在联合军事医院总医院耳鼻喉科进行。从耳鼻喉科OPD中选择了包括180名男女和所有年龄组的患者的便利样本。记录耳菌病的发生频率,诱发因素和最常见的症状。还观察到了对不同抗真菌剂的反应。结果以百分比记录。结果:180例确诊为真菌病的患者。男107(59%),女73(41%)。患者年龄从1岁到2岁不等。年至75岁,平均年龄38.5岁。平均随访时间为2年。最常见的症状是听力下降(77.7%),其次是瘙痒性炎(68.8%)和耳痛(40%)。我们对58%的患者开出1%克霉唑滴剂或洗剂的处方,对31%的患者开出2%水杨酸的处方剂。这两种药物都是有效的。局部用1%克霉唑滴眼液产生最高的分离率,复发率最低。共有149例(83%)患者接受初始治疗后有所改善,而31例(17%)对初始治疗无反应。 8名(4.4%)患者有耳科手术史。四名(2.2%)患者进行了管壁下陷手术,导致乳突腔。为了分析1%克霉唑和2%水杨酸的疗效,我们使用Z检验来计算治疗前2例患者与治疗后仍未治愈的患者之间的比例差异。结论:子宫内膜异位症通常表现为听力下降,瘙痒,瘙痒和耳痛和耳rr。通常可以通过局部洗耳和滴注抗真菌药来解决。在存在乳突腔和代谢性疾病(如mellitus.doi)的情况下,很难根除疾病:http://dx.doi.org/10.12669/pjms.303.4106如何引用此信息:Anwar K,Gohar MS。牙菌病;临床特征,诱发因素和治疗意义。 Pak J Med Sci 2014; 30(3):564-567。 doi:http://dx.doi.org/10.12669/pjms.303.4106这是根据知识共享署名许可(http://creativecommons.org/licenses/by/3.0)的条款分发的开放访问文章,允许在任何媒体中无限制地使用,分发和复制,但要正确引用原始作品。

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