From 1986 to 1990, sixty patients were treated for chronic osteomyelitis with surgery and chemotherapy. The clinical and radiologic follow-ups ranged from twelve to sixty months. The surgery was associated with a six-month oral sulfamethoxazole-trimethoprim combination chemotherapy. Clinical cure was achieved when inflammatory signs and symptoms disappeared, as happened to 50 (83.33%) of the single surgery cases, and to 9 (15%) of the multiple surgery cases. For one case (1.67%) osteomyelitis was not cured.
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