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首页> 外文期刊>Medicine. >Pneumonia Complicating Pandemic (H1N1) 2009: Risk Factors, Clinical Features, and Outcomes
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Pneumonia Complicating Pandemic (H1N1) 2009: Risk Factors, Clinical Features, and Outcomes

机译:2009年H1N1肺炎并发大流行:危险因素,临床特征和结果

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摘要

We performed an observational analysis of a prospective cohort of adults hospitalized for pandemic (H1N1) 2009 at 13 Spanish hospitals, from June to November 2009, to determine the risk factors, clinical features, and outcomes of pneumonia. Of 585 patients requiring hospitalization, chest radiography was obtained in 542. A total of 234 (43.1%) patients had pneumonia, of whom 210 underwent bacterial microbiologic studies. Of these patients, 174 (82.8%) had primary viral pneumonia and 36 (17.2%) had concomitant/secondary bacterial pneumonia. Bilateral pneumonia occurred in 48.3% of patients. Streptococcus pneumoniae was the most frequent pathogen among patients with bacterial pneumonia (26 of 36 patients). None of them had received pneumococcal vaccine. Compared with patients without pneumonia, those with pneumonia more frequently had shock during hospitalization (9.8% vs. 1%; p Abbreviations: BMI = body mass index, CAP = community-acquired pneumonia, CI = confidence interval, CURB-65 = confusion, urea, respiratory rate, blood pressure, and age ≥65 years, ICU = intensive care unit, OR = odds ratio, PSI = pneumonia severity index, ROC = receiver operating characteristic, RT-PCR = reverse-transcription polymerase chain reaction.
机译:我们对2009年6月至2009年11月在西班牙的13家医院中因2009年H1N1大流行而住院的成年人的预期队列进行了观察性分析,以确定肺炎的危险因素,临床特征和结局。在585例需要住院的患者中,有542例接受了X射线胸片检查。共有234例(43.1%)患有肺炎的患者,其中210例接受了细菌微生物学研究。在这些患者中,有174例(82.8%)患有原发性病毒性肺炎,而36例(17.2%)患有伴随/继发性细菌性肺炎。 48.3%的患者发生双侧肺炎。肺炎链球菌是细菌性肺炎患者中最常见的病原体(36名患者中有26名)。他们均未接种肺炎球菌疫苗。与没有肺炎的患者相比,患有肺炎的患者住院期间更容易出现休克(9.8%比1%; p缩写:BMI =体重指数,CAP =社区获得性肺炎,CI =置信区间,CURB-65 =意识模糊,尿素,呼吸频率,血压和年龄≥65岁,ICU =重症监护病房,OR =比值比,PSI =肺炎严重程度指数,ROC =受体工作特性,RT-PCR =逆转录聚合酶链反应。

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