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Stability Analysis of an Age-Structured SIR Epidemic Model with a Reduction Method to ODEs

机译:年龄结构化SIR流行病模型的ODE归约化方法稳定性分析

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In this paper, we are concerned with the asymptotic stability of the nontrivial endemic equilibrium of an age-structured susceptible-infective-recovered (SIR) epidemic model. For a special form of the disease transmission function, we perform the reduction of the model into a four-dimensional system of ordinary differential equations (ODEs). We show that the unique endemic equilibrium of the reduced system exists if the basic reproduction number for the original system is greater than unity. Furthermore, we perform the stability analysis of the endemic equilibrium and obtain a fourth-order characteristic equation. By using the Routh–Hurwitz criterion, we numerically show that the endemic equilibrium is asymptotically stable in some epidemiologically relevant parameter settings.
机译:在本文中,我们关注的是年龄结构的易感性感染恢复(SIR)流行病模型的非平凡流行平衡的渐近稳定性。对于疾病传播函数的一种特殊形式,我们将模型简化为一个常微分方程(ODE)的四维系统。我们表明,如果原始系统的基本再生数大于1,则简化系统的唯一地方性均衡存在。此外,我们进行了地方均衡的稳定性分析,并获得了四阶特征方程。通过使用Routh–Hurwitz准则,我们通过数值显示了在某些流行病学相关的参数设置中,地方平衡是渐近稳定的。

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