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Corrigendum: Impact of kinase activating and inactivating patient mutations on binary PKA interactions

机译:更正:激酶激活和失活患者突变对二元PKA相互作用的影响

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Reason for Corrigendum:There was a mistake in the figure legend for Figure 5 as published. The correct version of the figure legend (Figure 5B) appears below. The authors apologize for the mistake. This error does not change the scientific conclusions of the article in any way. Figure 5. Impact of RIa mutations and cAMP elevation on PKA type I complexes . … (B) Following indicated modifications of RIa-F[1] sequences, combinations of wild type and mutant R luc PCA tagged PKA subunits have been subjected to R luc PCA measurements. The effect of isoproterenol (1 μM, 10 min; 48 h transient PCA reporter expression) on PKA complex formation has been determined (at least n = 3 independent experiments, ±SEM).The original article was updated. Conflict of interest statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
机译:勘误的原因:图5中发布的图例中有一个错误。下面显示了图例的正确版本(图5B)。作者为这个错误表示歉意。此错误不会以任何方式改变本文的科学结论。图5. RIa突变和cAMP升高对PKA I型复合物的影响。 …(B)在指示的RIa-F [1]序列修饰之后,对野生型和突变R luc PCA标记的PKA亚基的组合进行了R luc PCA测量。确定了异丙肾上腺素(1μM,10分钟; 48 h PCA报告基因瞬时表达)对PKA复合物形成的影响(至少n = 3个独立实验,±SEM)。利益冲突声明作者宣称,这项研究是在没有任何商业或金融关系的情况下进行的,可以将其解释为潜在的利益冲突。

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