Complete Genome Sequence of Multidrug-Resistant Clinical Isolate Mycobacterium tuberculosis 187.0, Used To Study the Effect of Drug Susceptibility Reversion by the New Medicinal Drug FS-1

Aleksandr I. Ilin; Murat E. Kulmanov; Ilya S. Korotetskiy; Gulshara K. Akhmetova; Marina V. Lankina; Sergey V. Shvidko

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Complete Genome Sequence of Multidrug-Resistant Clinical Isolate Mycobacterium tuberculosis 187.0, Used To Study the Effect of Drug Susceptibility Reversion by the New Medicinal Drug FS-1

机译：耐多药临床分离结核分枝杆菌187.0的完整基因组序列，用于研究新药FS-1逆转药敏性的作用

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Complete genome sequence of the multidrug-resistant clinical isolate Mycobacterium tuberculosis SCAID 187.0 containing several drug-resistance mutations is presented. This strain is used in experiments to study genomic and population changes leading to reversion of susceptibility to the 1st line anti-tuberculosis (TB) drugs under the influence of a new medicinal drug FS-1.

机译：给出了多药耐药临床分离株结核分枝杆菌 SCAID 187.0的完整基因组序列，其中包含几个耐药突变。该菌株在实验中用于研究基因组和种群变化，从而导致在新药FS-1的影响下对一线抗结核（TB）药物的敏感性恢复。 展开▼

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《Genome Announcements》 |2015年第6期|共2页

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Aleksandr I. Ilin; Murat E. Kulmanov; Ilya S. Korotetskiy; Gulshara K. Akhmetova; Marina V. Lankina; Sergey V. Shvidko;
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中图分类基因工程（遗传工程）;

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1. Complete Genome Sequence of Multidrug-Resistant Clinical Isolate Mycobacterium tuberculosis 187.0, Used To Study the Effect of Drug Susceptibility Reversion by the New Medicinal Drug FS-1 [J] . Aleksandr I. Ilin, Murat E. Kulmanov, Ilya S. Korotetskiy, Genome Announcements . 2015,第6期

机译：耐多药临床分离结核分枝杆菌187.0的完整基因组序列，用于研究新药FS-1逆转药敏性的作用

2. Whole-Genome Sequences of Two Clinical Isolates of Extensively Drug-Resistant Mycobacterium tuberculosis from Zunyi, China [J] . Ling Chen, Derek T. Zhang, Jianyong Zhang, Genome Announcements . 2014,第5期

机译：遵义市两株广泛耐药结核分枝杆菌临床分离株的全基因组序列

3. Whole-Genome Sequences of Two Clinical Isolates of Extensively Drug-Resistant Mycobacterium tuberculosis from Zunyi, China [J] . Ling Chen, Derek T. Zhang, Jianyong Zhang, Genome Announcements . 2014,第5期

机译：遵义市两株广泛耐药结核分枝杆菌临床分离株的全基因组序列

4. Direct sequencing of inhA in mycobacterium tuberculosis Isolates resistant to multi-drugs [C] . Zhu Zhongyuan, Shao Hanshuang, Chen Yunfeng 7th China-Japan International Congress of Microbiology Shanghai Symposium-2000 4-6 August 2000 Shanghai . 2000

机译：结核分枝杆菌中inhA的直接测序对多药耐药的分离株

5. Annotation of hypothetical genes and mapping of insertion sequences in 51 de novo-assembled genomes of Mycobacterium tuberculosis clinical isolates [D] . Patel, Seema 2016

机译：结核分枝杆菌临床分离株51个从头组装基因组中假想基因的注释和插入序列的作图

6. Complete Genome Sequence of Multidrug-Resistant Clinical Isolate Mycobacterium tuberculosis 187.0 Used To Study the Effect of Drug Susceptibility Reversion by the New Medicinal Drug FS-1 [O] . Aleksandr I. Ilin, Murat E. Kulmanov, Ilya S. Korotetskiy, 2015

机译：耐多药临床分离结核分枝杆菌187.0的完整基因组序列用于研究新药FS-1逆转药敏性的作用

7. Assembly of Complete Genome Sequences of Negative-Control and Experimental Strain Variants of Staphylococcus aureus ATCC BAA-39 Selected under the Effect of the Drug FS-1, Which Induces Antibiotic Resistance Reversion [O] . Monique Joubert, Oleg N. Reva, Ilya S. Korotetskiy, 2019

机译：在药物FS-1作用下选择的葡萄球菌ATCC BAA-39的阴性对照和实验菌变型的完整基因组序列组装，诱导抗生素抗性逆转

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2. 耐多药肺结核与结核分枝杆菌L型感染的临床研究 [J] . 肖志坚 ,崔秀琴 ,胡天勇 . 河南医学研究 . 2002,第003期

3. 耐多药结核病及结核分枝杆菌耐多药分子机制的研究进展 [J] . 林辉 ,刘洁 ,曹佳 . 重庆医学 . 2006,第001期

4. 美罗培南联合克拉维酸对耐多药和广泛耐药结核分枝杆菌的作用 [J] . 陈旋 ,张炜 . 中华结核和呼吸杂志 . 2018,第001期

5. 棋盘法检测复治新方案核心药物对耐多药和广泛耐药结核分枝杆菌体外的联合作用 [J] . 张琳琳 ,杨华 ,肖和平 . 中华结核和呼吸杂志 . 2016,第006期

6. 肠胃清对人大肠癌耐长春新碱细胞株HCT8/V多药耐药的逆转作用 [C] . 许建华 ,邓皖利 ,范忠泽 . 第七届全国大肠癌学术会议暨第十届广东省大肠癌学术会议 . 2009

7. 耐多药肺结核与结核分枝杆菌L型感染的临床研究 [A] . 丁卫民 . 2003

1. 用于新药临床评价研究的大数据处理系统和方法 [P] . 中国专利： CN112562801A . 2021-03-26

2. MEDIUM COMPOSITION FOR DETECTING DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS, AND KIT FOR DETECTING DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS BY USING SAME [P] . 外国专利： WO2021261861A1 . 2021-12-30

机译：用于检测耐药性结核分枝杆菌的培养基组合物，并通过使用该试剂盒检测毒性结核分枝杆菌的试剂盒

3. IMPROVED QUANTAMATRIX ASSAY PLATFORM-BASED, DIAGNOSTIC METHOD CAPABLE OF SIMULTANEOUSLY IDENTIFYING DETECTION OF MYCOBACTERIUM TUBERCULOSIS AND RESISTANCE OF MYCOBACTERIUM TUBERCULOSIS TO RIFAMPIN, ISONIAZID, ETHAMBUTOL, QUINOLONE, SECOND LINE INJECTABLE DRUGS SUCH AS AMIKACIN, KANAMYCIN, AND CAPEOMYCIN, AND STREPTOMYCIN DRUGS, AND KIT THEREFOR [P] . 外国专利： WO2019225959A1 . 2019-11-28

机译：基于改进的量子矩阵分析平台的诊断方法，能够同时鉴定结核分枝杆菌的结核分枝杆菌，以及对结核分枝杆菌对利福平，异烟肼，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇和肌醇那个

4. DRUG RESISTANT TO MYCOBACTERIUM TUBERCULOSIS AND TO INFECTION WITH MYCOBACTERIUM TUBERCULOSIS, AND APPLICATION OF DRUG [P] . 外国专利： WO2018121499A1 . 2018-07-05

机译：结核分枝杆菌的抗药性和感染性

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Complete Genome Sequence of Multidrug-Resistant Clinical Isolate Mycobacterium tuberculosis 187.0, Used To Study the Effect of Drug Susceptibility Reversion by the New Medicinal Drug FS-1

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