Optimization for ultrasonic-assisted extraction of salidroside from Ligustrum lucidum by central composite design-response surface methodology

摘要

As a new extraction method, ultrasonic-assisted extraction (UAE), whose procedure has higher extraction yield, lower extracting temperature and less power consumption, was explored to extract salidroside from?Ligustrum lucidum?firstly. The content of salidroside was determined by reverse phase-high performance liquid chromatography (RP-HPLC). The UAE process of salidroside from?L. lucidum?was optimized by using central composite design-response surface methodology (CCD-RSM). The results showed that the optimal extraction conditions were ethanol concentration of 74.14%, liquid-solid ratio of 30.31, extracting time of 68.14 min and the extraction efficiency of salidroside was 4.68 mg;g-1. The results indicated that the UAE would be a novel method for extraction of salidroside from?L. lucidum.