Effects of Modafinil on Behavioral Learning and Hippocampal Synaptic Transmission in Rats

Wen-Wen Yan; Li-Hua Yao; Chong Chen; Hai-Xia Wang; Chu-Hua Li; Jun-Ni Huang; Peng Xiao; Cheng-Yi Liu

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Effects of Modafinil on Behavioral Learning and Hippocampal Synaptic Transmission in Rats

机译：莫达非尼对大鼠行为学习和海马突触传递的影响

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Purpose: Modafinil is a wake-promoting agent that has been proposed to improve cognitive performance at the preclinical and clinical levels. Since there is insufficient evidence for modafinil to be regarded as a cognitive enhancer, the aim of this study was to investigate the effects of chronic modafinil administration on behavioral learning in healthy adult rats.

机译：目的：莫达非尼是一种觉醒促进剂，已被提议在临床前和临床水平上改善认知能力。由于没有足够的证据将莫达非尼视为认知增强剂，因此本研究的目的是研究长期服用莫达非尼对健康成年大鼠行为学习的影响。

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《International Neurourology Journal》 |2015年第4期|共8页
作者
Wen-Wen Yan; Li-Hua Yao; Chong Chen; Hai-Xia Wang; Chu-Hua Li; Jun-Ni Huang; Peng Xiao; Cheng-Yi Liu;
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中图分类泌尿科学（泌尿生殖系疾病）;
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1. SYNAPTIC-LEARNING/BEHAVIORAL STATES CHARACTERIZING THE CONTRIBUTION OF HIPPOCAMPAL SYNAPSES TO ASSOCIATIVE LEARNING IN BEHAVING RATS [J] . Sanchez-Campusano R., Fernandez-Lamo I, Delgado-Garcia J. M., Acta physiologica . 2014,第Suppla698期

机译：突触学习/行为状态表征行为行为大鼠海马突触对联想学习的贡献
2. Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice [J] . Hitoshi Nagura, Yasuyuki Ishikawa, Katsunori Kobayashi, Molecular brain . 2012,第2期

机译：突触后密度蛋白的突触聚类受损和海马神经元信号传递改变，并破坏PDZ1和PDZ2配体结合缺陷型PSD-95敲入小鼠的学习行为
3. The Effects of Different Concentrations of the alpha(2)-Adrenoceptor Agonist Medetomidine on Basal Excitatory Synaptic Transmission and Synaptic Plasticity in Hippocampal Slices of Adult Mice [J] . Ribeiro Patricia O., Antunes Luis M., Nunes Catarina S., Anesthesia and Analgesia: Journal of the International Anesthesia Research Society . 2015,第5期

机译：不同浓度的α（2）-肾上腺素能受体激动剂美托咪定对成年小鼠海马切片基础兴奋性突触传递和突触可塑性的影响
4. Effects of microwave irradiation on hippocampal synaptic plasticity in vivo in rats [C] . Peng Xiao-dong, Liu Chuan-hui International EMF seminar in China: Electromagnetic fields and biological effects . 2000

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5. Effects of mitochondrial dysfunction on synaptic transmission in rat hippocampal slices. [D] . Kang, Eunji Ellen. 2005

机译：线粒体功能障碍对大鼠海马片突触传递的影响。
6. Effects of Modafinil on Behavioral Learning and Hippocampal Synaptic Transmission in Rats [O] . Wen-Wen Yan, Li-Hua Yao, Chong Chen, 2015

机译：莫达非尼对大鼠行为学习和海马突触传递的影响
7. Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice [O] . 2012

机译：突触后密度蛋白的突触聚类受损和海马神经元的信号传递发生改变，并破坏PDZ1和PDZ2配体结合缺陷型PSD-95敲入小鼠的学习行为
8. Effects of Anticholinesterase Agents on Synaptic Transmission in the In vitro and In vivo Pontine Reticular Formation: Electrophysiological Characterization of Medial Pontine Reticular Formation Neurons of the Rat Recorded In vitr [R] . Greene, R. W., McCarley, R. W. 1988

机译：抗胆碱酯酶药物对体外和体内脑桥网状结构突触传递的影响：玻璃体内记录的大鼠脑桥中网状神经元的电生理特征

Effects of Modafinil on Behavioral Learning and Hippocampal Synaptic Transmission in Rats

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