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首页> 外文期刊>International Journal of Pharmaceutical Sciences and Research >SLEEP QUALITY IN END-STAGE RENAL DISEASE PATIENTS ON MAINTENANCE HEMODIALYSIS: A SIX MONTH PROSPECTIVE SURVEY
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SLEEP QUALITY IN END-STAGE RENAL DISEASE PATIENTS ON MAINTENANCE HEMODIALYSIS: A SIX MONTH PROSPECTIVE SURVEY

机译:维持性血液透析终末期肾脏疾病患者的睡眠质量:六个月的预期调查

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Objective : The aim of this study was to evaluate the sleep quality and to identify risk factors for poor sleep quality in hemodialysis population. An additional aim of the study was to identify number of patients treated for their sleep problems. Method: 126 patients undergoing hemodialysis treatment were enrolled into the study. Subjective sleep quality was measured using Pittsburgh Sleep Quality Index. All the participants also completed Beck Depression Inventory questionnaire for evaluation of depressive symptoms. The pharmacotherapy and clinical, demographic and socioeconomic variables were also investigated. Results: Among the enrolled patients, poor sleep quality was reported in 67 % (n=85). Depressive symptoms were identified in 75% (n=62) of the poor sleepers. Significant association was observed between variables like being single, female gender, older age, low socioeconomic status, increased financial reliability, spending more than INR 10,000 ($ 166) per month for treatment, overweight, morning dialysis shift and dialysis duration more than 3 years. Clinical conditions like depression, diabetes, limb pain, fatigue, hypertension, hypoalbuminemia, hypocalcaemia and hypophosphatemia and use of medications like clonidine, erythropoietin, metoprolol and prazosin were also found to be associated with poor quality of sleep. Out of 67% (n=85) of the patients identified with sleep problems, 13% (n=17) were on sleep medications. Conclusion: The quality of sleep is impaired in hemodialysis population. Therefore, evaluation of sleep quality during regular clinical practice should be taken into consideration
机译:目的:本研究旨在评估血液透析人群的睡眠质量并确定不良睡眠质量的危险因素。该研究的另一个目的是确定因睡眠问题而接受治疗的患者人数。方法:将接受血液透析治疗的126例患者纳入研究。使用匹兹堡睡眠质量指数测量主观睡眠质量。所有参与者还完成了贝克抑郁量表问卷,以评估抑郁症状。还研究了药物治疗以及临床,人口和社会经济变量。结果:在入组患者中,报告睡眠质量差的比例为67%(n = 85)。在75%(n = 62)的不良睡眠者中发现了抑郁症状。观察到变量之间存在显着关联,例如单身,女性,年龄,社会经济地位低下,财务可靠性提高,每月治疗费用超过10,000印度卢比(166美元),超重,早上透析时间延长和透析时间超过3年。还发现诸如抑郁症,糖尿病,肢体疼痛,疲劳,高血压,低白蛋白血症,低钙血症和低磷酸盐血症等临床疾病以及使用可乐定,促红细胞生成素,美托洛尔和哌唑嗪等药物与睡眠质量差有关。在67%(n = 85)的有睡眠问题的患者中,有13%(n = 17)接受睡眠药物治疗。结论:血液透析人群的睡眠质量受损。因此,应考虑在常规临床实践中评估睡眠质量

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