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Tackling variation in the early stage evaluation of a state-wide integrated care program

机译:在州范围内的综合护理计划的早期评估中应对差异

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Introduction : Under the NSW ICS, the NSW Government has committed $180 million over six years to implementing innovative and locally led models of integrated care in NSW[1]. A challenge has been how best to approach the evaluation of these projects in order to capture learning and outcomes. The situation is confounded by the variation in care models and target populations observed across the demonstrator and innovator sites. Literature suggests that system level outcomes can take years to appear however there is a call for evidence on the impact integrated care investment has made to date. Methods : The study comprised all IC sites for which data was available – five in total (2960 patients). Using ANOVA and paired comparisons, we evaluated year-on-year differences in (1) the number of ED visits, and (2) length of stay for hospital admissions, for each patient, taking enrolment date as the point of reference and going back 4 years prior to that date. Year-on-year differences, as a self-referential metric for individual patients afford a more direct measure of efficacy in a heterogeneous cohort setting. It also results in a technically preferable Gaussian distribution as opposed to a Poisson distribution. To address the potential inferential complications arising from not having a control group, we devised a second study taking our inspiration from propensity matching, and capitalising on the opportunity created by the (quasi) step-wedge nature enrolment. Patients who have been in the program for 10 months or over were classified as the “intervention group” and those who have been in for 3 months or less were classified as the “control group”. A multiple linear regression was then performed with ICOD status and IC site as predictors. Results : In four of the five IC sites we studied, cohorts had an accelerating pattern of ED presentations for the four years prior to the IC program. In each case this accelerating pattern came to a halt with IC. This result was validated by the second study for all four sites. A multiple linear regression model for differential ED visits (against a pre-enrolment baseline) with intervention status and IC site as predictors confirmed IC intervention as a negative predictor for ED visits. As a rule, being in the intervention group meant a reduction in ED visits compared to the control group. For two of the four IC sites that showed a halt in ED presentations, similar analyses of unplanned overnight hospital admissions reveal year-on-year increases not only come to a halt but are reversed with intervention. Total length of stay is also reduced for these cohorts. Conclusion : The results provide evidence of early stage impact by the IC program in four of the five LHDs we evaluated. The study also illustrates a practical application of statistical learning methods capable of extracting evidence of early stage impact from a state-wide heterogeneous set of care models.
机译:简介:在新南威尔士州立大学(ICS)的领导下,新南威尔士州政府承诺在六年内投入1.8亿澳元,在新南威尔士州实施创新的,由当地领导的一体化医疗模式[1]。一个挑战是如何最好地进行这些项目的评估,以获取学习和成果。在演示者和创新者场所观察到的护理模型和目标人群的差异,使情况感到困惑。文献表明,系统级结果可能要花费数年才能显现出来,但是,需要证据证明迄今为止综合护理投资已产生了影响。方法:本研究包括可获得数据的所有IC站点-总共5个(2960例患者)。使用方差分析和配对比较,我们以入院日期作为参考点并回顾了以下方面的差异:(1)每位患者的急诊就诊次数和(2)住院时间长短在该日期之前的4年。逐年差异作为个体患者的自我参照指标,可以在异质队列中提供更直接的疗效度量。与泊松分布相反,这也导致了技术上更佳的高斯分布。为了解决由于没有对照组而引起的潜在推断性并发症,我们设计了第二项研究,从倾向匹配中汲取了灵感,并利用了(准)渐进式自然入学所创造的机会。参加该计划10个月或以上的患者被分类为“干预组”,参加了3个月或以下的患者被分类为“对照组”。然后以ICOD状态和IC部位为预测指标进行多元线性回归。结果:在我们研究的五个IC站点中的四个中,在IC计划之前的四年中,队列中的ED呈现加速模式。在每种情况下,IC都停止了这种加速模式。第二个研究针对所有四个站点验证了这一结果。针对差异性ED访视(针对入学前基线)的多元线性回归模型,其中干预状态和IC部位为预测因素,证实IC干预为ED访视的阴性预测因素。通常,与对照组相比,参与干预组意味着ED访视减少。对于在ED演示中止的四个IC站点中的两个,对计划外的过夜医院入院的类似分析表明,同比增长不仅停止,而且在干预后被逆转。这些人群的总住院时间也减少了。结论:结果提供了我们评估的五个LHD中的四个LIC早期阶段影响的证据。该研究还说明了统计学习方法的实际应用,该方法能够从全州范围不同的护理模型集中提取早期影响的证据。

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