The effect of vitamin C on bone mineral density of menopausal women with equilibrated regime: A randomized clinical trial study, 2012-2013

摘要

The objective of the current study was to estimate the effect of vitamin C on BMD in menopausal women with balanced dietary. In the randomized controlled clinical trial, 150 menopausal women suffering from osteoporosis were chosen in purposive sampling method. In randomized block design, the individuals were placed in the received vitamin C (test) and placebo (control) groups. After integrating groups, the test group received 1000 mg of vitamin C in two divided doses for 6 months and the placebo control group received in the same method. There was a significant correlation between obstetric history with lumbar BMD (r= -295 and p<0.001) and femoral BMD (r= -0.226 and p=0.006). The average index changes of vertebral bone density did not indicate a statistically significant difference in the vitamin C group (0.02±0.05, P=0.001) and the placebo group (0.02±0.04, P<0.001) before and after treatment. With respect to the findings of the study about the effects of vitamin C on BMD, antioxidant is suggested to add to the current treatments.DOI: http://dx.doi.org/10.3126/ijls.v8i4.10930