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Physical activity and sedentary behaviour in relation to cardiometabolic risk in children: cross-sectional findings from the Physical Activity and Nutrition in Children (PANIC) Study

机译:与儿童心脏代谢风险有关的体育锻炼和久坐行为:儿童体育锻炼与营养(PANIC)研究的横断面研究

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Background Lower levels of physical activity (PA) and sedentary behaviour (SB) have been associated with increased cardiometabolic risk among children. However, little is known about the independent and combined associations of PA and SB as well as different types of these behaviours with cardiometabolic risk in children. We therefore investigated these relationships among children. Methods The subjects were a population sample of 468 children 6–8 years of age. PA and SB were assessed by a questionnaire administered by parents and validated by a monitor combining heart rate and accelerometry measurements. We assessed body fat percentage, waist circumference, blood glucose, serum insulin, plasma lipids and lipoproteins and blood pressure and calculated a cardiometabolic risk score using population-specific Z-scores and a formula waist circumference?+?insulin?+?glucose?+?triglycerides - HDL cholesterol?+?mean of systolic and diastolic blood pressure. We analysed data using multivariate linear regression models. Results Total PA was inversely associated with the cardiometabolic risk score (β?=?-0.135, p?=?0.004), body fat percentage (β?=?-0.155, p?
机译:背景较低的体力活动(PA)和久坐行为(SB)与儿童心脏代谢风险增加有关。然而,关于PA和SB的独立和联合关联以及这些行为的不同类型与儿童的心脏代谢风险知之甚少。因此,我们调查了儿童之间的这些关系。方法研究对象是468名6-8岁儿童的人口样本。 PA和SB由父母提供的问卷进行评估,并由结合了心率和加速度测量的监测仪进行验证。我们评估了体脂百分比,腰围,血糖,血清胰岛素,血浆脂质和脂蛋白以及血压,并使用人群特异性Z评分和公式腰围?+“胰岛素” +“葡萄糖” +来计算心脏代谢风险评分。 “甘油三酸酯-HDL胆固醇” +“收缩压和舒张压的平均值”。我们使用多元线性回归模型分析了数据。结果总PA与心脏代谢风险评分(β≥=-0.135,p≥= 0.004),体脂百分比(β≥=-0.155,p≤<0.001),胰岛素(β≥= 0.001)呈负相关。 -0.099,p = 0.034,β=β-0.166,p << 0.001,甘油三酯(βDL=β-0.230,p <0.001),DLDL,β-胆固醇;βDL=β-0.001。 -0.168,p?=?0.001),LDL胆固醇(β?=?-0.094,p?=?0.046)和HDL甘油三酸酯(β?=?-0.149,p?=?0.004),与HDL胆固醇直接相关(根据年龄和性别调整后的β?=?0.144,p?=?0.002)。非结构化PA与心脏代谢风险评分(β?=?-0.123,p?=?0.010),体脂百分比(β?=?-0.099,p?=?0.027),胰岛素(β?=?- 0.108,p?=?0.021),甘油三酸酯(β?=?-0.144,p?=?0.002),VLDL甘油三酸酯(β?=?-0.233,p?<?0.001)和VLDL胆固醇(β?=?- 0.199,p≤0.001,并且与HDL胆固醇直接相关(β= 0.126,p = 0.008)。看电视和录像与心脏代谢风险评分(β≥0.135,p≥0.003),体脂百分比(β≥0.090,p≥0.039),腰围(β≥0.05)直接相关。 0.097,p = 0.033,收缩压(β= 0.096,p = 0.039)。休息与心脏代谢风险评分(β?=?0.092,p?=?0.049),甘油三酯(β?=?0.131,p?=?0.005),VLDL甘油三酯(β?=?0.134,p?= (0.009),VLDL胆固醇(β≥0.147,p≥0.004)和LDL胆固醇(β≥0.105,p≥0.023)。其他类型的PA和SB与心脏代谢风险因素的相关性较弱。结论我们的研究结果强调增加总的和非结构化的PA并减少观看电视和视频以及其他久坐的行为,以降低儿童的心脏代谢风险。试验注册ClinicalTrials.gov标识符:NCT01803776。

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