Isolation and Antimicrobial Susceptibility Patterns ofCampylobacterSpecies among Diarrheic Children at Jimma, Ethiopia

摘要

Introduction.Campylobacteris one of the leading bacterial causes of food-borne disease. The prevalence ofCampylobacterspecies resistant to antimicrobial agents is increasing. This study is intended to determine prevalence and antimicrobial susceptibility patterns ofCampylobacterspecies among under-five children with diarrhea.Methodology. A cross-sectional study was conducted among 227 under-five children with diarrhea from July to October 2012 at Jimma town. Isolation and identification ofCampylobacterspecies were performed using standard bacteriological techniques. Antimicrobial susceptibility test was performed following standard protocol. Chi-square and Fisher’s exact tests were used for analysis.Results. From 227 under-five children, 16.7% were positive forCampylobacterspp.; isolates,C. jejuni,C. coli, andC. lari, accounted for 71.1%, 21.1%, and 7.9%, respectively. Higher rate of resistance was observed to ampicillin 76.3%, trimethoprim-sulfamethoxazole (68.4%), tetracycline (39.5%), chloramphenicol (31.6%), clindamycin (26.3%), and doxycycline (23.7%). Erythromycin, ciprofloxacin, gentamicin, norfloxacin, and nalidixic acid were effective for more than 80% of the isolates. Multiple drug resistance was observed among 78.9% of all the three spp.Conclusions. Isolation rate ofCampylobacterspp. was high.C. lariwas reported for the first time at this study area. Higher rate of resistance was observed to the commonly used drugs.