Left atrial volume index as an indicator of left ventricular diastolic dysfunction and hypertrophy

摘要

Background: This study was performed to point out a possiblecorrelation between left atrial volume index (LAVI) and left ventriculardiastolic dysfunction and hypertrophy (LVH).Methods: In 200 patients without LV systolic dysfunction, leftatrial volume and LV wall thickness were measured by 2D Echocardiography.LAVI was calculated by dividing LAV by BSA (bodysurface area). LV diastolic dysfunction was calculated by usingdifferent parameters (IVRT, DT, E/A ratio). 100 controls were takento obtain the reference values. 99% of test cohort patients werehypertensive.Patients with low EF, significant mitral valve diseaseor recent MI were excluded from study cohort.Results: Results showed a statistically significant correlation betweenleft atrial volume and left ventricular hypertrophy (pvalue<0.001). LAVI had a linear correlation with grades of diastolicdysfunction.Higher grades of diastolic dysfunction was associatedwith larger LA volume.Increased LV Mass was also associated withhigher LAVI.Conclusions: LAVI appear to be a reliable tool to noninvasivelycategorise patients (mostly hypertensive) to have increased LVmass and higher grades of diastolic dysfunction and to identify atrisk patient who have high chance of developing diastolic heartfailure in future.