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STUDY OF GLYCATED HEMOGLOBIN LEVELS IN POLYCYSTIC OVARY SYNDROME

机译:多囊卵巢综合征糖化血红蛋白水平的研究

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Objective: Polycystic ovarian syndrome (PCOS) is often accompanied by insulin resistance, obesity, and cardiometabolic risk factors. Androgen excess-PCOS recommends oral glucose tolerance test or glycated hemoglobin (HbA1C) to evaluate dysglycemia in PCOS subjects. We undertook this study to evaluate the prevalence of elevated HbA1C levels in PCOS women. Methods: The study was carried out among 100 PCOS patients from SRM Hospital, 100 healthy individuals were included as controls. Fasting glucose, HbA1C, Insulin and Homeostasis Model Assessment-Insulin Resistance Index were estimated. Results: Patients with polycystic ovary syndrome showed a significant increase in HbA1C levels (5.799±1.022; 4.96±0.625, p=0.001) when compared to the control group. Conclusion: We found elevated HbA1C levels in PCOS women categorizing 26% as prediabetes and 28% as having type 2 diabetes mellitus.
机译:目的:多囊卵巢综合征(PCOS)常常伴有胰岛素抵抗,肥胖和心脏代谢危险因素。雄激素过多的PCOS建议进行口服葡萄糖耐量测试或糖化血红蛋白(HbA1C)来评估PCOS受试者的血糖异常。我们进行了这项研究,以评估PCOS妇女中HbA1C水平升高的患病率。方法:本研究在SRM医院的100例PCOS患者中进行,其中100例健康人作为对照组。估计空腹血糖,HbA1C,胰岛素和体内稳态模型评估-胰岛素抵抗指数。结果:与对照组相比,多囊卵巢综合征患者的HbA1C水平显着增加(5.799±1.022; 4.96±0.625,p = 0.001)。结论:我们发现PCOS妇女中HbA1C水平升高,分为26%为糖尿病前期和28%为2型糖尿病。

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