A case of metastatic renal cell carcinoma treated effectively by gemcitabine and sunitinib

摘要

A 60-year-old man with renal cell carcinoma developedlung metastases after treatment with left radicalnephrectomy (pT3bN0M0, clear cell renal carcinoma,Fuhrman G3 >2). The patient received treatment withgemcitabine and interferon-α and achieved completeresponse after seven cycles of therapy. However, eightmonths later, local recurrence was discovered in therenal fossa. We changed the therapeutic strategy tosunitinib, a multi-target tyrosine kinase inhibitor. Thepatient achieved a complete response after twelve cyclesof therapy. This case report illustrates the effective useof gemcitabine and sunitinib sequentially for a patientwith metastatic renal cell carcinoma