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Outcomes and effectiveness of bilateral percutaneous transluminal renal artery stenting in patients with critical bilateral renal artery stenosis

机译:严重双侧肾动脉狭窄患者双侧经皮腔内肾动脉支架置入术的结果和有效性

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Background: The aim of this study was to assess the effects of percutaneous bilateral renal artery stenting in patients with atherosclerotic renal artery stenosis and in-hospital and 4 month outcome of the procedure, focusing on the changes in renal function and blood pressure. Methods: Five consecutive patients (mean age: 64.8 ± 9.7 years, 1 women) with bilateral renal artery stenoses underwent percutaneous interventions. We compared blood pressure, number of oral antihypertensive medications, and renal function changes preprocedure and postprocedure at 4 months follow-up. Results: A total of 5 bilateral atherosclerotic renal artery stenosis patients underwent percutaneous transluminal renal angioplasty and 10 stents were placed. Although systolic and diastolic blood pressures were significantly decreased in follow-up period, glomerular filtration rates were not significantly changed as compared with baseline data (p = 0.009, p = 0.008, p = 1.00, respectively). Also, the number of oral antihypertensive medications were significantly decreased at follow-up period (p = 0.03). Conclusions: Bilateral renal artery stenting provides a beneficial outcome such as stabilization of renal functions, significant improvement in blood pressure control and reduction in the number of oral antihypertensive medications at follow-up.
机译:背景:本研究的目的是评估经皮双侧肾动脉支架置入术对动脉粥样硬化性肾动脉狭窄和住院及术后4个月结果的影响,重点是肾功能和血压的变化。方法:连续五例双侧肾动脉狭窄患者(平均年龄:64.8±9.7岁,1名女性)接受了经皮介入治疗。我们比较了术后4个月的血压,口服降压药的数量以及术前和术后肾功能的变化。结果:总共5例双侧动脉粥样硬化性肾动脉狭窄患者接受了经皮腔内肾血管成形术,并放置了10个支架。尽管在随访期间收缩压和舒张压显着降低,但与基线数据相比,肾小球滤过率没有显着变化(分别为p = 0.009,p = 0.008,p = 1.00)。此外,在随访期间口服降压药的数量也明显减少(p = 0.03)。结论:双侧肾动脉支架置入术可提供有益的结果,例如稳定肾功能,显着改善血压控制和减少随访时口服降压药的数量。

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